On average, at any given time, an American Alligator has between 74 and 80 teeth. As teeth break or wear out, alligators grow replacements from teeth stem cells. Alligators can replace each tooth up to 50 times during their 35- to 75-year lives. In contrast, humans have two sets of 32 teethâ€¦and no replacements. Maybe thatâ€™s why we brush, floss and take care of our teeth and alligators donâ€™t?